Focus on the various corridors of snake bite envenomation treatment- A review

Mishal, H. B., Mishal, R. H. and Saudagar, R. B.

Snake bite is an important and serious global health issue. Till date anti snake venom serum is the only therapeutic remedy available for treating the snake bite victims. Infusion of ASV may lead to adverse reactions ranging from pruritus, urticaria to potentially fatal anaphylaxis. The development of ASV is also a costly and time consuming process requiring ideal storage conditions. Though Anti Snake Venom Serum (ASV) is the only remedy available to treat snake bite victims successfully till date, considering all above difficulties research workers all over the world are constantly in search of a cheap and readily available easy formulate remedy for treating snake bite victims. A few chemical constituents of the plants have been so far identified for their anti snake venom effect. Traditional remedies from plants used in the treatment of snakebite victims have a number of potential advantages over the ASVs. Considering these limited number of published reports, one can say that many such plants which can provide potent immunization against snake bite poisoning are yet to be evaluated systematically. Research is also being carried nowadays to produce the immunity against the specific snake venom by using a targeted drug delivery system. Much emphasis is also given on the correct detection of types of venoms injected in the body of the victim and successful rehabilitation of patients after treatment. One can say that a permanent and suitable protection against any snake bite poisoning will be fulfilled in the near future and liposomes may become the way for developing a new and effective anti snake venom dosage form. In the present paper some of the aspects of snake bite treatment from ASVs to the recently developed measures of detecting snake bite envenomation and therapies have been discussed.

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